Verified July 2026 · Cited to primary sources
CJC-1295 / Ipamorelin: Evidence Grade C — Early / foreign human data only.
The honest verdict
CJC-1295/Ipamorelin is not FDA-approved and is not legally compoundable (CJC-1295 withdrawn April 2026). Human evidence is Grade C — one PK study proves it raises GH/IGF-1, but no trial shows muscle or fat-loss benefit. Researching CJC-1295 on its own (often "with DAC")? See our standalone CJC-1295 page.
CJC-1295 / Ipamorelin at a glance
- Class
- GHRH analog (CJC-1295) stacked with a selective GH secretagogue (Ipamorelin)
- Mechanism
- CJC-1295 (a GHRH analog) drives sustained pituitary GH/IGF-1 release while Ipamorelin (a selective ghrelin/GHS-R agonist) adds a clean GH pulse — the stack aims to raise GH/IGF-1.
- Also known as
- CJC-1295 (Mod-GRF 1-29), CJC-1295 DAC, Ipamorelin stack
- Research applications
- Muscle growth and body recomposition (marketed; no efficacy RCT)
- GH optimization / anti-aging (claimed; unproven)
- Forms
- subcutaneous injection
- Legal status
- Research-only
- WADA (anti-doping)
- Prohibited (S2 — GHRH analog / GH secretagogue) at all times
- Evidence grade
- Grade CEarly / foreign human data only
How we grade evidence
Every grade is assigned by a fixed A–F rubric — human-trial strength, not hype or affiliate status. Last verified July 6, 2026.
What is CJC-1295 / Ipamorelin?
The classic GH-boosting stack — one human PK study shows it raises GH/IGF-1, but no trial shows it builds muscle or burns fat.
CJC-1295 (a GHRH analog) drives sustained pituitary GH/IGF-1 release while Ipamorelin (a selective ghrelin/GHS-R agonist) adds a clean GH pulse — the stack aims to raise GH/IGF-1.
How strong is the evidence for CJC-1295 / Ipamorelin?
Graded to the stronger component. CJC-1295 has one published human PK study showing GH/IGF-1 elevation (Grade C — early human data, rule 4). Ipamorelin has only limited early-phase human development (Grade D). Neither has an efficacy RCT for muscle, fat, or anti-aging — the marketed benefits are unproven.
Primary sources (4)
Is CJC-1295 / Ipamorelin legal? (Status July 2026)
No legal supervised US route.
What is CJC-1295 / Ipamorelin used for?
CJC-1295 / Ipamorelin is marketed for the goals below. See how it ranks against other peptides in each — by evidence, not hype.
What does CJC-1295 / Ipamorelin cost — and how do you access it legally?
Typical cost
$200–$400/month (stack)
CJC-1295/Ipamorelin stack pricing ~$200–$400/month (~$445/cycle) per seekpeptides.com; access is gray-market given the 503A status.
No legal supervised access route right now.
CJC-1295 / Ipamorelin has no compliant US route today. Vials sold "for research use only" are a gray-market fig-leaf, not a legal loophole — we don't link them. If you pursue CJC-1295 / Ipamorelin, do it with a licensed clinician, and re-check its legal status first.
Is CJC-1295 / Ipamorelinsafe? Side effects & risks
GH-excess effects (edema, carpal tunnel, insulin resistance, IGF-1 elevation → theoretical cancer risk). A widely-cited adverse-event report exists for CJC-1295 DAC (causation unestablished). CJC-1295 nomination was withdrawn April 2026; Ipamorelin's status is conflicting/rejected. WADA-prohibited (S2).
Medical disclaimer: This page is independent editorial information, not medical advice, and Best Peptide For That is not a medical provider. We do not provide dosing. Talk to a licensed clinician before starting, stopping, or changing any peptide or medication. Full medical disclaimer.
FAQ
CJC-1295 / Ipamorelin FAQ
Is this the same as CJC-1295 on its own?
No. This page covers the popular stack — CJC-1295 (a GHRH analog) combined with Ipamorelin (a separate ghrelin/GH-secretagogue peptide). For CJC-1295 by itself, usually the long-acting "with DAC" version, see our dedicated CJC-1295 page.
Does CJC-1295/Ipamorelin build muscle?
There is no human trial showing it builds muscle or burns fat. The only human data is a pharmacokinetic study confirming it raises GH and IGF-1 levels — that is why we grade it C, not higher.
Is CJC-1295/Ipamorelin legal to get from a clinic?
Not through a compliant 503A route. CJC-1295's compounding nomination was withdrawn in April 2026 and PCAC previously voted against it, so it is effectively research-only. Any clinic openly selling it today is a compliance flag.
Is it banned in sport?
Yes. Both are on the WADA Prohibited List under S2 (GHRH analogs and GH secretagogues).
Compare CJC-1295 / Ipamorelin with…
Head-to-head evidence-grade matchups people weigh against CJC-1295 / Ipamorelin.
Keep reading
CJC-1295
A GHRH analog — usually the long-acting "with DAC" version — that one human study shows raises GH/IGF-1, but no trial shows it builds muscle or burns fat.
Grade BSermorelin
The "gentler," formerly-FDA-approved GH-axis peptide — the best-evidenced option you can still legally get through a compounding pharmacy.
Grade ATesamorelin
One of only two FDA-approved peptides in this space — proven to cut visceral fat, but approved for a narrow HIV indication.
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